Overview
Cushing’s disease occurs when the adrenal glands overproduce cortisol, the stress hormone. It’s usually caused by a pituitary gland tumor (85%) or adrenal tumor (15%). Excess cortisol weakens muscles, thins the skin, suppresses the immune system, and predisposes to diabetes, pancreatitis, and urinary infections. It develops gradually and is often mistaken for normal aging.
Symptoms to Watch For
- Excessive drinking and urination
- Pot-bellied appearance
- Panting and heat intolerance
- Thinning skin and hair loss (especially on body, not legs)
- Recurrent skin and urinary infections
How Nutrition Helps
Moderate-protein, low-fat diets support muscle maintenance while managing the metabolic disruption caused by excess cortisol. Controlling sodium helps manage the increased thirst and blood pressure. Antioxidants (vitamin E, vitamin C) combat the oxidative stress caused by chronically elevated cortisol. Omega-3 fatty acids support skin health, which deteriorates significantly with Cushing’s.
How Activity Helps
Gentle, regular exercise helps maintain weakened muscles. Avoid overexertion as Cushing’s dogs fatigue easily and overheat quickly.
Prevention Tips
- Annual blood panels for middle-aged and senior dogs
- Don’t dismiss increased drinking and urination as just aging
- Monitor for pot-bellied appearance and hair loss
- Limit long-term steroid use when possible
- Regular vet visits for early detection
Breeds at Higher Risk
Poodles, Dachshunds, Boston Terriers, Boxers, Beagles, and Yorkshire Terriers. Most common in dogs over 6 years.